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KMID : 0377619710200040337
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Korean Jungang Medical Journal
1971 Volume.20 No. 4 p.337 ~ p.342
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Histological Study on the Lymp Nodes from Neonatal and Adult Pigs.
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Abstract
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As the experimental animals, the miniature pigs of Minnesota University were used. Germ-free piglets obtained by aseptic hysterectomy three to five days prior to term were kept in germ-free unit during the period of experiment. Those animals were sacrificed by bleeding and we took regional lymph nodes, that is mesenteric lymph node,
cervical lymph node, sub maxillary lymph node and inguinal lymph node from them. Using hematoxylin and eosin staining, methyl-green pyronin staining and silver staining methods, we examined them under the microscope.
Then we had results as following:
1. In the pigs, the trabeculae of the lymph node developed and branched into the lymph node connecting the capsule at the hilus of the lymph node; while in other species, the trabeculae of lymph node developed into the lymph node from many places of capsule of the lymph node.
2. Cortical substances including germinal center were developed following the trabeculae of the lymph node and medullary substances were located in the periphery of the lymph node.
3. The light zone of germinal center and small lymphocytes surrounding it placed themselves toward the near side of the trabeculae; on the other hand, the dark zone placed itself toward the far side of the trabeculae.
4. Those results suggested that the lymph flowed into lymph node through trabeculae or subtrabecular sinus in the pigs.
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